Healthy oral microbiome contributes to jaw bone health by influencing immune cell interactions with bone cells
Researchers have shown that commensal microbes in the mouth, in contrast to commensal microbes colonizing other body surfaces, e.g., the gut or skin, modulate immune responses in the jaw bone that promote bone-resorbing osteoclasts and bone loss. In a preclinical model, depleting healthy commensal microbes in the mouth, using an antiseptic oral rinse, was shown to protect against this bone loss.
